Opioid Analgesics MC II Year

Opioid analgesics are prescribed for moderate to severe pain, particularly of visceral origin. Evidence of efficacy and safety is strongest for use in acute pain and cancer-related pain. They are used…

Continue Reading Opioid Analgesics MC II Year

Phytosomes HDT III Year

Phytosome is a patented technology that involves chemical interactions between phospholipids and water soluble herbal compounds, suitable as drug delivery systems for topical and oral administration. From: Lipid Nanocarriers for Drug…

Continue Reading Phytosomes HDT III Year

Estimation of Km & Vmax BPPK III Year

Km and Vmax are determined by incubating the enzyme with varying concentrations of substrate; the results can be plotted as a graph of rate of reaction (v) against concentration of substrate ([S], and…

Continue Reading Estimation of Km & Vmax BPPK III Year

Structure and uses of Alcohols POC I Year

Water and alcohols have similar properties because water molecules contain hydroxyl groups that can form hydrogen bonds with other water molecules and with alcohol molecules, and likewise alcohol molecules can form hydrogen bonds with other alcohol molecules as…

Continue Reading Structure and uses of Alcohols POC I Year

Folate reductase inhibitors MC III Year

Pyrimethamine and trimethoprim are the most widely used dihydrofolate reductase inhibitors. Pyrimethamine is a known terattogen but is more effective then trimethoprim, which is usually administered in conjunction with a dihydropteroate…

Continue Reading Folate reductase inhibitors MC III Year

Factors of Nonlinearity Part II BPPK- III Year

Causes of Nonlinearity 1. Drug Absorption Three causes: I) Solubility / dissolution of drug is rate-limited; Griseofulvin - at high concentration in intestine. II) Carrier - mediated transport system; Ascorbic acid -…

Continue Reading Factors of Nonlinearity Part II BPPK- III Year

Sulfonamides: Sulfisoxazole MC III Year

Sulfisoxazole is a sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms. It has a role as an antibacterial drug and a drug…

Continue Reading Sulfonamides: Sulfisoxazole MC III Year