Synthesis Sulfonamides: Synthesis of Sulphanilamide MC III Year

Principle: Sulphanilamide can beprepared by taking acetanilide and treating it with excess of chlorosulphonic acid, which gives p-acetamidobenzenesulphonyl chloride which readily converted into corresponding p-acetamidobenzenesulphonamides upon reaction with ammonia or ammonium carbonate.

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