Anthelmintic Drugs MC III Year

Introduction to anthelmintics
The helminths comprise two major groups of multicellular worms that evolved from a common
ancestor some 600 million years ago and diverged into two rather different groups. The
nemathelminths (nematodes, roundworms) and the platyhelminths (flatworms). The latter
group is subdivided into the trematodes (flukes) and the cestodes (tapeworms). Almost 350
species of helminths have been found in humans, and most colonise the gastrointestinal tract.
Helminths have a complex life cycle, often involving several species. Infection by helminths
may occur in many ways, and poor hygiene is a major contributory factor.

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