Anti Protozoal Agents. Metronidazole MC III Years

Antiprotozoal agents

Antiprotozoal therapy must be comprehensive and should cover all likely pathogens in the context of the clinical setting. In the treatment of trichomoniasis, 5-nitroimidazole drugs are the only widely used antiprotozoal agents.  5-Nitroimidazoles are believed to disrupt the helical structure of DNA in trichomonads, ultimately leading to cell death.  The exact mechanisms of many antiprotozoal agents, including 5-nitroimidazoles, are not well understood.

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